Advice for PDX???

I originally posted this over at the new toycamera.com forums, but then thought to cross-post it here for possible wider exposure.

My wife & I are planning a week long sojourn to Portland, OR later this fall as a kind of interview with the Rose City to see if it’ll fit as a possible relocation locale (the long heavy winters of upstate NY are getting to be a bit too much).

As such, we want to be as thorough as a week allows. Instead of hitting up touristy stuff, we want to try to see the city as a local would.

So any advice from native Portlanders or transplants (or anyone else familiar with the town, for that matter) on what to do, what to see, where to eat, et cetera?

Any help would be greatly appreciated.